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Nardil is an antidepressant and an anxiolytic that is generally used for the treatment of major depressive disorders such as bipolar depression, panic disorder, social anxiety disorder, dysthymia, bulimia, and post-traumatic stress disorder. Technically, it is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) related to the drugs tranylcypromine and isocarboxazid. Nardil is also among the few nonselective MAOIs that continue to have widespread clinical use. The drug works by stimulating various brain chemicals that are low in depressed people.
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Nardil's generic name is Phenelzine sulfate, and it contains major ingredients including croscarmellose sodium, mannitol, and magnesium stearate. The recommended initial dosage for patients is 15 mg thrice daily.
Some of the most common adverse effects associated with Nardil are dizziness, blurred vision, headache, lethargy, dry mouth, nausea, vomiting, and diarrhea. In a few rare cases, however, it can actually increase the risk of suicidal thinking and behavior.
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The early days of Nardil. This magazine ad was printed in the 50's, back when MAOIs were first starting to be marketed to the general public. "A true antidepressant" indeed... and much more effective than the glorified placebos they try ...